Invention Grant
- Patent Title: Fully human antibodies against human 4-1BB
-
Application No.: US14211438Application Date: 2014-03-14
-
Publication No.: US09382328B2Publication Date: 2016-07-05
- Inventor: Maria Jure-Kunkel , Laura J. Hefta , Marc Santoro , Subinay Ganguly , Edward L. Halk
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Stephen C. D'Amico
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; C07K16/30 ; A61K39/00 ; A61K39/12 ; A61K39/39
Abstract:
Fully human antibodies and antigen-binding portions thereof that bind to human 4-1BB and that allow binding of human 4-1BB to a human 4-1BB ligand. In one aspect, the antibody is an IgG4 antibody. Also provided is a method for treating a disease in a subject comprising administering a therapeutically effective amount of the antibody to said subject.
Public/Granted literature
- US20140193422A1 FULLY HUMAN ANTIBODIES AGAINST HUMAN 4-1BB Public/Granted day:2014-07-10
Information query
