发明授权
- 专利标题: Iodine-containing radial-shaped macromolecular compounds, preparation method thereof and contrast media compositions for CT comprising the same
- 专利标题(中): 含碘的径向大分子化合物,其制备方法和包含其的CT的造影剂组合物
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申请号: US13816846申请日: 2011-08-16
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公开(公告)号: US09387267B2公开(公告)日: 2016-07-12
- 发明人: Yoonkyung Kim , Dong-Eog Kim , Hye-Youn Jung , Yun Hui Choe
- 申请人: Yoonkyung Kim , Dong-Eog Kim , Hye-Youn Jung , Yun Hui Choe
- 申请人地址: KR Daejeon
- 专利权人: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
- 当前专利权人: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
- 当前专利权人地址: KR Daejeon
- 代理机构: Lucas & Mercanti, LLP
- 优先权: KR10-2010-0078060 20100813; KR10-2011-0080912 20110812
- 国际申请: PCT/KR2011/006002 WO 20110816
- 国际公布: WO2012/021046 WO 20120216
- 主分类号: A61K51/06
- IPC分类号: A61K51/06 ; A61K49/10 ; A61K49/12 ; A61K49/14 ; A61K49/04
摘要:
Disclosed herein is an iodine-containing radial-shaped macromolecule suitable for an active ingredient of the computed tomography (CT) contrast medium, a method to prepare the same, and a contrast medium composition including the same. With respect to the iodine-containing radial-shaped macromolecule according to the present invention, the duration of contrast enhancement has been significantly improved in comparison to that of the current small molecular contrast media compounds containing iodine.
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