Invention Grant
- Patent Title: Arginine methyltransferase inhibitors and uses thereof
- Patent Title (中): 精氨酸甲基转移酶抑制剂及其用途
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Application No.: US14213144Application Date: 2014-03-14
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Publication No.: US09394258B2Publication Date: 2016-07-19
- Inventor: Richard Chesworth , Lorna Helen Mitchell , Gideon Shapiro , Kevin Wayne Kuntz
- Applicant: Epizyme, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Epizyme, Inc.
- Current Assignee: Epizyme, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Wolf, Greenfield & Sacks, P.C.
- Main IPC: A61K31/44
- IPC: A61K31/44 ; A61K31/415 ; C07D401/00 ; C07D231/56 ; C07D401/12 ; C07D403/12 ; C07D401/04 ; C07D405/04 ; C07D405/12
Abstract:
Described herein are compounds of Formula (I), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting arginine methyltransferase activity. Methods of using the compounds for treating arginine methyltransferase-mediated disorders are also described.
Public/Granted literature
- US20140288124A1 ARGININE METHYLTRANSFERASE INHIBITORS AND USES THEREOF Public/Granted day:2014-09-25
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