Invention Grant
- Patent Title: Indole and indazole compounds that activate AMPK
- Patent Title (中): 激活AMPK的吲哚和吲唑化合物
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Application No.: US14773954Application Date: 2013-09-24
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Publication No.: US09394285B2Publication Date: 2016-07-19
- Inventor: Samit Kumar Bhattacharya , Kimberly O'Keefe Cameron , Matthew Scott Dowling , David Christopher Ebner , David James Edmonds , Dilinie Prasadhini Fernando , Kevin James Filipski , Daniel Wei-Shung Kung , Esther Cheng Yin Lee , Aaron Christopher Smith , Meihua Mike Tu
- Applicant: Pfizer Inc.
- Applicant Address: US NY New York
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NY New York
- Agent James T. Wasicak
- Priority: WOPCT/IB2013/052604 20130401
- International Application: PCT/IB2013/058819 WO 20130924
- International Announcement: WO2014/140704 WO 20140918
- Main IPC: C07D405/12
- IPC: C07D405/12 ; C07D403/12 ; C07D401/04 ; C07D401/12 ; A61K31/404 ; A61K31/4439 ; A61K31/454 ; A61K31/496 ; A61P13/12 ; A61P3/10
Abstract:
The present invention relates to indole and indazole compounds of Formula (I) that activate 5′ adenosine monophosphate-activated protein kinase (AMPK). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating or preventing diseases, conditions, or disorders ameliorated by activation of AMPK.
Public/Granted literature
- US20160016940A1 Indole and Indazole Compounds that Activate AMPK Public/Granted day:2016-01-21
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