A multi physical properties part used in automotive components required to be lightweight and provide collision safety, and a method of manufacturing a multi physical properties part, in which the multi physical properties part may be more economically and simply manufactured by using two or more separated die sets without using an additional heating device or treating a die surface. A method of manufacturing a multi physical properties part, which includes positioning a single heated formed article in two or more die sets, and then manufacturing a multi physical properties part including two or more regions having different physical properties by differing cooling conditions in the respective die set.