发明授权
- 专利标题： Composition for prophylaxis or treatment of vascular or cardiac valvular calcification comprising dipeptidyl peptidase-4 inhibitor
- 专利标题（中）： 包含二肽基肽酶-4抑制剂的预防或治疗血管或心脏瓣膜钙化的组合物
-
申请号： US14473618申请日： 2014-08-29
-
公开(公告)号： US09416196B2公开(公告)日： 2016-08-16
- 发明人: Jae Kwan Song , Eun Ju Chang , Mi Jeong Kim , Bongkun Choi , Sahmin Lee
- 申请人： THE ASAN FOUNDATION
- 申请人地址： KR Seoul KR Ulsan
- 专利权人： THE ASAN FOUNDATION,UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
- 当前专利权人： THE ASAN FOUNDATION,UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION
- 当前专利权人地址： KR Seoul KR Ulsan
- 代理机构： Hultquist, PLLC
- 代理商 Steven J. Hultquist
- 优先权： KR10-2013-0103189 20130829
- 主分类号： A61K31/70
- IPC分类号： A61K31/70 ; C07K16/44 ; A61K31/4985 ; A61K31/7105 ; A61K31/713 ; A61K38/06 ; C12N5/00
摘要：
There is provided a composition for prophylaxis or treatment of vascular or valvular calcification including a dipeptidylpeptidase-4 (DPP-4) inhibitor. The DPP-4 according to one exemplary embodiment of the present disclosure is expressed at an increased level when blood vessels and valves are calcified, and the calcification decreases remarkably upon administration of the DPP-4 inhibitor. Therefore, the DPP-4 inhibitor can be useful in treatment or prophylaxis of blood vessels or valves.
公开/授权文献
信息查询
