Invention Grant
- Patent Title: Long-acting interferon beta formulation comprising an immunoglobulin fragment
- Patent Title (中): 包含免疫球蛋白片段的长效干扰素β制剂
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Application No.: US13638821Application Date: 2011-04-04
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Publication No.: US09421244B2Publication Date: 2016-08-23
- Inventor: Dae Jin Kim , Min Young Kim , Jin Sun Kim , Sung Hee Hong , Sung Youb Jung , Se Chang Kwon
- Applicant: Dae Jin Kim , Min Young Kim , Jin Sun Kim , Sung Hee Hong , Sung Youb Jung , Se Chang Kwon
- Applicant Address: KR Hwaseong-si
- Assignee: HANMI SCIENCE CO., LTD
- Current Assignee: HANMI SCIENCE CO., LTD
- Current Assignee Address: KR Hwaseong-si
- Agency: Sughrue Mion, PLLC
- Priority: KR10-2010-0030577 20100402
- International Application: PCT/KR2011/002335 WO 20110404
- International Announcement: WO2011/122923 WO 20111006
- Main IPC: A61K38/21
- IPC: A61K38/21 ; A61K47/48 ; C07K14/565 ; C07K19/00
Abstract:
The present invention relates to a long-acting interferon beta formulation having improved in vivo duration and stability, comprising an interferon beta conjugate that is prepared by covalently linking interferon beta with an immunoglobulin Fc region via a non-peptidyl polymer, and a preparation method thereof. The long-acting interferon beta formulation of the present invention maintains in vivo activity of interferon beta at a relatively high level and remarkably increases the serum half-life thereof, thereby being used for various diseases, for which interferon is efficacious.
Public/Granted literature
- US20130028867A1 LONG-ACTING INTERFERON BETA FORMULATION USING IMMUNOGLOBULIN FRAGMENT Public/Granted day:2013-01-31
Information query
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