Abstract:
Techniques for assisting a designer in correcting discrepancies identified in layout design data. A user interface may be provided listing identified shorts and relevant information related to those shorts. Still further, the user interface may allow a designer to selectively choose a subset of the identified shorts, and to designate or otherwise provide correction data for use to correct the shorts before performing a short isolation process on the selected shorts. Alternately or additionally a user interface may provide a designer with graphical images showing the correction that should be made by a designer to address an identified discrepancy in layout design data.
Abstract:
The present invention provides a system for processing a semiconductor substrate using a laser beam, the system including: a storing unit storing a process control data set for a slot for loading the semiconductor substrate therein; a process controlling unit detecting identification information of the slot in which the semiconductor substrate is loaded, and reading the control data, which is set for the detected identification information, from the storing unit to control a process of the semiconductor substrate; and a substrate processing unit processing the semiconductor substrate on the basis of the read control data using the laser beam with a predetermined energy.
Abstract:
Disclosed are an Fc fragment modified by a non-peptide polymer, a pharmaceutical composition comprising the Fc fragment modified by the non-peptide polymer as a carrier, a complex of the Fc fragment and a drug via a linker and a pharmaceutical composition comprising such a complex. The Fc fragment modified by a non-peptide peptide according to the present invention lacks immunogenicity and effector functions. Due to these properties, the Fc fragment maintains the in vivo activity of a drug conjugated thereto in high levels, remarkably increases the serum half-life of the drug, and remarkably reduces the risk of inducing immune responses.
Abstract:
The present invention relates to an insulinotropic peptide conjugate having improved in-vivo duration of efficacy and stability, comprising an insulinotropic peptide, a non-peptide polymer and a carrier substance, which are covalently linked to each other, and a use of the same. The insulinotropic peptide conjugate of the present invention has the in-vivo activity which is maintained relatively high, and has remarkably increased blood half-life, and thus it can be desirably employed in the development of long acting formulations of various peptide drugs.
Abstract:
An HDTV receiver is disclosed including a tuning portion for selecting one of a plurality of RF signals received, and converting a selected RF signal into an intermediate frequency signal; a demodulator/FPLL for demodulating the intermediate frequency signal output from the tuning portion into a baseband signal in which the frequency and phase are locked, and outputting an AFC signal; a first local oscillator for forming a frequency signal which can be varied from a reference frequency to a specific frequency, and outputting the thus-formed frequency signal to the demodulator/FPLL; and a VSB filter for VSB-filtering the baseband signal output from the demodulator/FPLL.
Abstract:
The present invention relates to a non-peptidyl polymer-insulin multimer comprising two or more of a non-peptidyl polymer-insulin conjugate prepared by linking a non-peptidyl polymer and insulin via a covalent bond, in which the conjugates are complexed with cobalt ion to form a multimer, a method and kit for the preparation of the multimer, a pharmaceutical composition for the prevention or treatment of diabetes comprising the multimer as an active ingredient, and a method for preventing or treating diabetes by administering the composition to a subject.
Abstract:
The present invention relates to a non-peptidyl polymer-insulin multimer comprising two or more of a non-peptidyl polymer-insulin conjugate prepared by linking a non-peptidyl polymer and insulin via a covalent bond, in which the conjugates are complexed with cobalt ion to form a multimer, a method and kit for the preparation of the multimer, a pharmaceutical composition for the prevention or treatment of diabetes comprising the multimer as an active ingredient, and a method for preventing or treating diabetes by administering the composition to a subject.
Abstract:
The present invention relates to a long-acting interferon beta formulation having improved in vivo duration and stability, comprising an interferon beta conjugate that is prepared by covalently linking interferon beta with an immunoglobulin Fc region via a non-peptidyl polymer, and a preparation method thereof. The long-acting interferon beta formulation of the present invention maintains in vivo activity of interferon beta at a relatively high level and remarkably increases the serum half-life thereof, thereby being used for various diseases, for which interferon is efficacious.
Abstract:
A turbo-machine including a volute casing, a rotating shaft, an impeller, seals, an axial thrust control member and a bellows unit. The volute casing defines therein a fluid passage. The rotating shaft is rotatably provided in the volute casing. The impeller is coupled to the rotating shaft to draw fluid using centrifugal force. The seals are provided around the front and rear ends of the impeller to prevent leakage of fluid. The axial thrust control member is installed in the volute casing behind the impeller. The bellows unit includes the piston installed in the volute casing in a shape surrounding a circumferential outer surface of the axial thrust control member; and a bellows connected with one surface of the piston, the bellows having the predetermined elasticity; and an internal space, between the piston and the volute casing, isolated from the fluid drawn behind the impeller.
Abstract:
The turbo-machine of the present invention includes a volute casing, a rotating shaft, an impeller, seals, an axial thrust control member and a bellows unit. The volute casing defines therein a fluid passage. The rotating shaft is rotatably provided in the volute casing. The impeller is coupled to the rotating shaft to draw fluid using centrifugal force. The seals are provided around the front and rear ends of the impeller to prevent leakage of fluid. The axial thrust control member is installed in the volute casing behind the impeller. The bellows unit includes the piston installed in the volute casing in a shape surrounding a circumferential outer surface of the axial thrust control member; and a bellows connected with one surface of the piston, the bellows having the predetermined elasticity; and an internal space, between the piston and the volute casing, isolated from the fluid drawn behind the impeller.