Invention Grant
- Patent Title: Benzopiperazine compositions as BET bromodomain inhibitors
- Patent Title (中): 苯并哌嗪组合物作为BET溴代寡核苷酸抑制剂
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Application No.: US14546896Application Date: 2014-11-18
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Publication No.: US09422281B2Publication Date: 2016-08-23
- Inventor: Kenneth W. Bair , Torsten Herbertz , Goss S. Kauffman , Katherine J. Kayser-Bricker , George P. Luke , Matthew W. Martin , David S. Millan , Shawn E. R. Schiller , Adam C. Talbot , Mark J. Tebbe
- Applicant: Forma Therapeutics, Inc.
- Applicant Address: US MA Watertown
- Assignee: Forma Therapeutics, Inc.
- Current Assignee: Forma Therapeutics, Inc.
- Current Assignee Address: US MA Watertown
- Agency: Cooley LLP
- Main IPC: C07D241/12
- IPC: C07D241/12 ; A61K31/53 ; C07D471/04 ; C07D403/04 ; A61K31/498 ; C07D405/14 ; C07D417/14 ; C07D417/10 ; C07D241/42 ; C07D409/14 ; C07D405/06 ; C07D413/14 ; C07D413/04 ; C07D401/04 ; C07D403/14 ; A61K31/4985 ; A61K31/5377 ; A61K31/541 ; A61K31/551
Abstract:
The present invention relates to inhibitors of bromo and extra terminal (BET) br’omodomains that are useful for the treatment of cancer, inflammatory diseases, diabetes, and obesity, having Formula (I): wherein X, Y, Z, R1, R2, R4 and R7 are defined herein.
Public/Granted literature
- US20150232465A1 BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS Public/Granted day:2015-08-20
Information query
