发明授权
US09422307B2 2,4,7-substituted thieno[3,2-d]pyrimidine compounds as protein kinase inhibitors
有权
2,4,7-取代的噻吩并[3,2-d]嘧啶化合物作为蛋白激酶抑制剂
![2,4,7-substituted thieno[3,2-d]pyrimidine compounds as protein kinase inhibitors](/docs/US/2016-08-23/US09422307B2/abs.jpg.600x600.jpg)
- 专利标题： 2,4,7-substituted thieno[3,2-d]pyrimidine compounds as protein kinase inhibitors
- 专利标题（中）： 2,4,7-取代的噻吩并[3,2-d]嘧啶化合物作为蛋白激酶抑制剂
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申请号： US13510743申请日： 2010-10-22
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公开(公告)号： US09422307B2公开(公告)日： 2016-08-23
- 发明人: Tae Bo Sim , Jung Mi Hah , Hwan Geun Choi , Young Jin Ham , Jung Hun Lee , Dong Sik Park , Hwan Kim
- 申请人： Tae Bo Sim , Jung Mi Hah , Hwan Geun Choi , Young Jin Ham , Jung Hun Lee , Dong Sik Park , Hwan Kim
- 申请人地址： KR Seoul
- 专利权人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- 当前专利权人： KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
- 当前专利权人地址： KR Seoul
- 代理机构： Goldilocks Zone IP Law
- 优先权： KR10-2009-0112132 20091119
- 国际申请： PCT/KR2010/007275 WO 20101022
- 国际公布： WO2011/062372 WO 20110526
- 主分类号： C07D495/04
- IPC分类号： C07D495/04 ; A61K31/519 ; A61P35/04
![2,4,7-substituted thieno[3,2-d]pyrimidine compounds as protein kinase inhibitors](/abs-image/US/2016/08/23/US09422307B2/abs.jpg.150x150.jpg)
摘要：
A substituted thieno pyrimidine compound of Formula 1, pharmaceutically acceptable salts and a pharmaceutical composition thereof is provided. The compound of Formula 1 exhibits superior inhibition activity against various protein kinases involved in growth factor signal transduction. The compound of Formula 1 and its compositions are useful for the prevention and treatment of diseases caused by abnormal cell growth including cancer.
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