A vaporizer filler includes a fill port. The fill port defines an open interior. The open interior is configured to receive the nozzle of an anesthetic bottle. An agent reservoir is configured to receive and store anesthetic agent. A valve is disposed between the open interior and the agent reservoir. At least one vent extends through the fill port. A method of filling a vaporizer includes inserting the nozzle of a bottle filled with anesthetic agent into a vaporizer filler. At least one vent is occluded from fluid communication. Fluid communication between and open interior and an agent reservoir is opened. Anesthetic agent is poured into an agent reservoir of a vaporizer. Fluid communication is closed between the open interior and the agent reservoir. At least one vent is opened to fluid communication with the open interior. Pressure within the open interior is released through the at least one vent.