Invention Grant
- Patent Title: 5-azaindazole compounds and methods of use
- Patent Title (中): 5-氮杂吲唑化合物及其使用方法
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Application No.: US13927278Application Date: 2013-06-26
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Publication No.: US09434725B2Publication Date: 2016-09-06
- Inventor: Steven Do , Huiyong Hu , Aleksandr Kolesnikov , Vickie H. Tsui , Xiaojing Wang
- Applicant: Genentech, Inc.
- Applicant Address: CH Basel
- Assignee: F. HOFFMANN-LA ROCHE AG
- Current Assignee: F. HOFFMANN-LA ROCHE AG
- Current Assignee Address: CH Basel
- Agency: Alston & Bird LLP
- Main IPC: C07D471/04
- IPC: C07D471/04 ; C07D471/10 ; C07D487/10 ; C07D491/052 ; A61K31/496 ; A61K31/551 ; A61K31/4545 ; A61K31/497 ; A61K31/513 ; A61K31/444 ; A61K31/55 ; A61K45/06 ; A61K31/501

Abstract:
5-Azaindazole compounds of Formula I, including stereoisomers, geometric isomers, tautomers, and pharmaceutically acceptable salts thereof, are useful for inhibiting Pim kinase, and for treating disorders such as cancer mediated by Pim kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, prevention or treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.
Public/Granted literature
- US20140005168A1 5-AZAINDAZOLE COMPOUNDS AND METHODS OF USE Public/Granted day:2014-01-02
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