Invention Grant
- Patent Title: Production method for organic acid using CoA-transferase
- Patent Title (中): 使用CoA转移酶的有机酸的生产方法
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Application No.: US14351497Application Date: 2012-10-10
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Publication No.: US09434965B2Publication Date: 2016-09-06
- Inventor: Ken'ichiro Matsumoto , Seiichi Taguchi , Hirobumi Aoki
- Applicant: SHOWA DENKO K.K. , NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
- Applicant Address: JP Tokyo JP Sapporo-shi
- Assignee: SHOWA DENKO K.K.,NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
- Current Assignee: SHOWA DENKO K.K.,NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITY
- Current Assignee Address: JP Tokyo JP Sapporo-shi
- Agency: Sughrue Mion, PLLC
- Priority: JP2011-228751 20111018; JP2012-063097 20120321
- International Application: PCT/JP2012/076194 WO 20121010
- International Announcement: WO2013/058150 WO 20130425
- Main IPC: C12P7/42
- IPC: C12P7/42

Abstract:
The present invention relates to a method of producing organic acids, comprising biochemical synthesis of organic acid-CoA using acetyl-CoA as a substrate and conducting CoA elimination reaction of the organic acid-CoA using CoA transferase in the presence of acetic acid, in which organic acid is obtained by culturing transformed microorganisms which have an enzyme gene cluster for the synthesis of organic acid-CoA using acetyl-CoA as a substrate and a CoA transferase gene.
Public/Granted literature
- US20140234927A1 PRODUCTION METHOD FOR ORGANIC ACID USING COA-TRANSFERASE Public/Granted day:2014-08-21
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