Invention Grant
US09439898B2 Methods for novel drug discovery, treatment and selective targeting for gefitinib-resistant non-small-cell lung cancer harboring T790M mutation
有权
新型药物发现,治疗和选择性靶向吉非替尼耐药性非小细胞肺癌携带T790M突变的方法
- Patent Title: Methods for novel drug discovery, treatment and selective targeting for gefitinib-resistant non-small-cell lung cancer harboring T790M mutation
- Patent Title (中): 新型药物发现,治疗和选择性靶向吉非替尼耐药性非小细胞肺癌携带T790M突变的方法
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Application No.: US14296477Application Date: 2014-06-05
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Publication No.: US09439898B2Publication Date: 2016-09-13
- Inventor: Elaine Lai-Han Leung , Liang Liu , Xing-Xing Fan
- Applicant: Macau University of Science and Technology
- Applicant Address: MO Macau
- Assignee: Macau University of Science and Technology
- Current Assignee: Macau University of Science and Technology
- Current Assignee Address: MO Macau
- Agency: Ella Cheong Hong Kong
- Agent Sam T. Yip
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; A61K31/4741 ; A61K33/40 ; G01N33/50

Abstract:
The present invention relates to methods for novel drug discovery, treatment and selective targeting for Gefitinib-resistant non-small-cell lung cancer (NSCLC) harboring an additional mutation, in particular, to the discovery of a drug candidate or agent identified by the presently claimed method for use in treating and selective targeting Gefitinib-resistant NSCLC harboring T790M mutation.
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