发明授权
- 专利标题： Fluorescent cyanine-polyamine derivatives as a diagnostic probe
- 专利标题（中）： 荧光花青多胺衍生物作为诊断探针
-
申请号： US13822535申请日： 2011-11-24
-
公开(公告)号： US09439982B2公开(公告)日： 2016-09-13
- 发明人: Yves Guminski , Thierry Imbert , Sabrina Pesnel , Arnaud Pillon , Alain Le Pape , Stephanie Lerondel
- 申请人： Yves Guminski , Thierry Imbert , Sabrina Pesnel , Arnaud Pillon , Alain Le Pape , Stephanie Lerondel
- 申请人地址： FR Boulogne-Billancourt FR Paris
- 专利权人： PIERRE FABRE MEDICAMENT,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
- 当前专利权人： PIERRE FABRE MEDICAMENT,CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS)
- 当前专利权人地址： FR Boulogne-Billancourt FR Paris
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： FR1059687 20101124
- 国际申请： PCT/EP2011/070980 WO 20111124
- 国际公布： WO2012/069607 WO 20120531
- 主分类号： A61B5/00
- IPC分类号： A61B5/00 ; A61B8/00 ; A61B10/00 ; A61K49/00 ; C07D209/14 ; C07D403/06
摘要：
The invention relates to fluorescent derivatives of cyanines conjugated with a polyamine group, having formula (I), or a pharmaceutically acceptable salt thereof. The invention also relates to the method for preparing said derivatives, diagnostic compositions containing same and the use thereof as a diagnostic probe for the detection of cancer tumors, in particular in vivo.