Decompression panel assemblies and methods of equalizing air pressure differential are provided. The decompression panel assembly includes a panel comprising an opening defined therein, a vent cover coupled across the opening, and a latching mechanism. The vent cover is configured to move between a first position and a second position. The latching mechanism is configured to maintain the vent cover in the first position when a pressure differential across the panel is below a predetermined value and facilitate the vent cover moving to the second position when the pressure differential across the panel exceeds the predetermined value.