Invention Grant
US09440973B2 Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione derivatives
有权
吡啶并[3,4-d]嘧啶-2,4(1H,3H) - 二酮衍生物
- Patent Title: Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione derivatives
- Patent Title (中): 吡啶并[3,4-d]嘧啶-2,4(1H,3H) - 二酮衍生物
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Application No.: US14822232Application Date: 2015-08-10
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Publication No.: US09440973B2Publication Date: 2016-09-13
- Inventor: Bertrand L. Chenard , Randall J. Gallaschun
- Applicant: Hydra Biosciences, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Hydra Biosciences, Inc.
- Current Assignee: Hydra Biosciences, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Kathryn M. Kizer
- Main IPC: A61K31/519
- IPC: A61K31/519 ; C07D471/04
![Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione derivatives](/abs-image/US/2016/09/13/US09440973B2/abs.jpg.150x150.jpg)
Abstract:
This invention relates to novel Pyrido[3,4-d]pyrimidine-2,4(1H,3H)-dione derivatives of Formula (I): and their use as TRPC5 modulators, pharmaceutical compositions containing the same, and methods of using the same as agents for the treatment of TRPC5 receptor mediated disorders or conditions. R1, R2, R3 and R4 have meanings given in the description.
Public/Granted literature
- US20160039815A1 PYRIDO[3,4-d]PYRIMIDINE-2,4(1H,3H)-DIONE DERIVATIVES Public/Granted day:2016-02-11
Information query
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