Invention Grant
- Patent Title: Substituted 1,3-thiazoles as heat shock transcription factor 1 activators
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Application No.: US14878749Application Date: 2015-10-08
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Publication No.: US09447058B2Publication Date: 2016-09-20
- Inventor: Dennis J. Thiele , Daniel W. Neef , Jose S. Mendoza
- Applicant: Duke University , Chaperone Therapeutics, Inc.
- Applicant Address: US NC Durham US NC Durham
- Assignee: Duke University,Chaperone Therapeutics, Inc.
- Current Assignee: Duke University,Chaperone Therapeutics, Inc.
- Current Assignee Address: US NC Durham US NC Durham
- Agency: Casimir Jones, SC
- Main IPC: C07D277/42
- IPC: C07D277/42 ; A61K31/415 ; A61K31/4155 ; A61K31/426 ; A61K45/06 ; C07D231/40 ; C07D277/60 ; C07D409/04 ; C07K14/47 ; C07C211/01 ; C07D231/38 ; C07D277/38 ; C07D405/14 ; C07D413/12
Abstract:
The present invention relates to 1,3-thiazole compounds, methods for their discovery, and their research and therapeutic uses, as well as pharmaceutically acceptable salts, solvates, chelates, non-covalent complexes, prodrugs, mixtures (including both R and S enantiomeric forms and racemic mixtures thereof), and pharmaceutical Formulations thereof.
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