Invention Grant
US09447439B2 Microorganism producing 4-hydroxybutyrate and a method for producing 4-hydroxybutyrate in anaerobic condition using the same
有权
生产4-羟基丁酸的微生物和使用该4-羟基丁酸在厌氧条件下生产4-羟基丁酸的方法
- Patent Title: Microorganism producing 4-hydroxybutyrate and a method for producing 4-hydroxybutyrate in anaerobic condition using the same
- Patent Title (中): 生产4-羟基丁酸的微生物和使用该4-羟基丁酸在厌氧条件下生产4-羟基丁酸的方法
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Application No.: US14468067Application Date: 2014-08-25
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Publication No.: US09447439B2Publication Date: 2016-09-20
- Inventor: Youngmin Lee , Wooyong Lee , Jinwoo Kim , Jaechan Park , Jinhwan Park , Hwayoung Cho
- Applicant: Samsung Electronics Co., Ltd.
- Applicant Address: KR Suwon-Si
- Assignee: SAMSUNG ELECTRONICS CO., LTD.
- Current Assignee: SAMSUNG ELECTRONICS CO., LTD.
- Current Assignee Address: KR Suwon-Si
- Agency: Leydig, Voit & Mayer, Ltd.
- Priority: KR10-2013-0100568 20130823
- Main IPC: C12P7/42
- IPC: C12P7/42 ; C12N9/00 ; C12P7/46 ; C12N9/02 ; C12P17/04
Abstract:
A genetically modified microorganism comprising a polynucleotide encoding α-ketoglutarate synthase or a mutant thereof, and a polynucleotide encoding pyruvate carboxylase or a mutant thereof; wherein the genetically modified microorganism has decreased malate quinone oxidoreductase activity and/or decreased phosphoenolpyruvate carboxykinase activity compared to an unmodified microorganism of the same type, and wherein the genetically modified microorganism produces 4-hydroxybutyrate.
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