发明授权
US09448296B2 Motion-sensitized driven equilibrium blood-suppression sequence for vessel wall imaging
有权
运动敏化的驱动平衡血液抑制序列用于血管壁成像
- 专利标题: Motion-sensitized driven equilibrium blood-suppression sequence for vessel wall imaging
- 专利标题(中): 运动敏化的驱动平衡血液抑制序列用于血管壁成像
-
申请号: US12922257申请日: 2009-02-20
-
公开(公告)号: US09448296B2公开(公告)日: 2016-09-20
- 发明人: Jinnan Wang , Vasily Yarnykh , Chun Yuan
- 申请人: Jinnan Wang , Vasily Yarnykh , Chun Yuan
- 申请人地址: US WA Seattle
- 专利权人: University of Washington
- 当前专利权人: University of Washington
- 当前专利权人地址: US WA Seattle
- 代理机构: Kilpatrick Townsend and Stockton LLP
- 国际申请: PCT/US2009/034686 WO 20090220
- 国际公布: WO2009/117211 WO 20090924
- 主分类号: A61B5/05
- IPC分类号: A61B5/05 ; G01R33/56 ; G01R33/561 ; G01R33/563
摘要:
An improved motion-sensitization driven equilibrium (iMSDE) sequence based upon an MLEV-4 sequence is used for black-blood vessel wall imaging. The MSDE pulse pattern that is used us a preparation sequence for other procedures employed to acquire images has been modified to produce the iMSDE sequence by the addition of a second 180 degree refocusing pulse and two motion sensitization gradients. The iMSDE sequence thus includes a group of four radio frequency (RF) pulses, as well as additional magnetic gradient pulses that are not included in the conventional MSDE sequence. Computer simulations indicate that this new pulse sequence is substantially more immune to local B1 inhomogeneity than conventional sequences. In vivo experiments have demonstrated significant signal improvement at high first-order moments (m1) conditions compared to the traditional MSDE sequence.
公开/授权文献
信息查询