A method and a device for managing resources of a base station in a wireless communication system is provided. The method comprises: calculating an average resource use of serving resources, which are used as downlinks from a serving base station to a plurality of communication terminals; selecting one of the communication terminals, which has a maximum interference from a neighbor base station, if the calculated average resource use exceeds a preset threshold; and making a reservation for at least one of neighbor resources used as downlinks from the neighbor base station, the at least one neighbor resource corresponding to the serving resource for the selected communication terminal, so that the neighbor base station may decrease transmission power in the at least one neighbor resource.