发明授权
- 专利标题： Genetically detoxified pertussis vaccine that maintains intrinsic adjuvant activity
- 专利标题（中）： 基因解毒的百日咳疫苗维持内在的佐剂活性
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申请号： US14800126申请日： 2015-07-15
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公开(公告)号： US09452213B2公开(公告)日： 2016-09-27
- 发明人: Subhash V. Kapre
- 申请人： Subhash V. Kapre
- 申请人地址： US WA Redmond
- 专利权人： Inventprise, LLC
- 当前专利权人： Inventprise, LLC
- 当前专利权人地址： US WA Redmond
- 代理机构： Remenick PLLC
- 主分类号： A61K39/39
- IPC分类号： A61K39/39 ; A61K39/02 ; A61K39/00
摘要：
The invention is directed to a method for the production of a pertussis vaccine and, in particular, a detoxified pertussis vaccine comprising detoxified pertussis toxin (PT), detoxified pertussis lipopolysaccharide (P-LPS), and detoxified pertussis adenylate cyclase toxin (P-ACT). The invention is also directed to the manufacture of a vaccine or the invention and methods for the administration of a detoxified vaccine to patients.
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