发明授权
US09452927B2 Nanofluidic biosensor and its use for rapid measurement of biomolecular interactions in solution and methods
有权
纳米流体生物传感器及其在溶液和方法中快速测量生物分子相互作用的应用
- 专利标题： Nanofluidic biosensor and its use for rapid measurement of biomolecular interactions in solution and methods
- 专利标题（中）： 纳米流体生物传感器及其在溶液和方法中快速测量生物分子相互作用的应用
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申请号： US13511805申请日： 2010-11-19
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公开(公告)号： US09452927B2公开(公告)日： 2016-09-27
- 发明人: Nicolas Durand , Yannick Fournier , Theo Lasser , Iwan Märki
- 申请人： Nicolas Durand , Yannick Fournier , Theo Lasser , Iwan Märki
- 申请人地址： CH Lausanne
- 专利权人： ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
- 当前专利权人： ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
- 当前专利权人地址： CH Lausanne
- 代理机构： Nixon & Vanderhye P.C.
- 优先权： CH1824/09 20091127
- 国际申请： PCT/IB2010/055305 WO 20101119
- 国际公布： WO2011/064701 WO 20110603
- 主分类号： G01N33/558
- IPC分类号： G01N33/558 ; B82Y15/00 ; B01L3/00 ; B82Y35/00 ; G01N21/64
摘要：
A method and device for the rapid detection of biomolecules (320) diffusing in a nanometer-confined slit (204) is claimed. In particular, the present invention relates to a novel concept of fluidic side apertures (205) that facilitates the filling of the device, the surface coating with biomolecules and that measures the affinity between fluorescently labeled biomolecules in aqueous solution with other biomolecules immobilized on surfaces.
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