发明授权
- 专利标题： Selective inhibitors of undifferentiated cells
- 专利标题（中）： 未分化细胞的选择性抑制剂
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申请号： US14402467申请日： 2013-05-22
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公开(公告)号： US09456998B2公开(公告)日： 2016-10-04
- 发明人: Uri Ben-David , Nissim Benvenisty , Payal Arora , Qing-Fen Gan , Ralph J. Garippa
- 申请人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. , Hoffmann-La Roche Inc.
- 申请人地址： IL Jerusalem US NJ Little Falls
- 专利权人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.,Hoffmann-La Roche Inc.
- 当前专利权人： Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.,Hoffmann-La Roche Inc.
- 当前专利权人地址： IL Jerusalem US NJ Little Falls
- 国际申请： PCT/IL2013/050441 WO 20130522
- 国际公布： WO2013/175474 WO 20131128
- 主分类号： A61K31/4409
- IPC分类号： A61K31/4409 ; A61K31/15 ; A61K31/34 ; A61K31/403 ; A61K31/407 ; A61K31/4453 ; A61K31/4545 ; A61K31/4985 ; A61K31/136 ; A61K31/155 ; A61K31/165 ; A61K31/166 ; A61K31/341 ; A61K31/343 ; A61K31/381 ; A61K31/4015 ; A61K31/404 ; A61K31/451 ; A61K31/513 ; G01N33/50
摘要：
Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.
公开/授权文献
- US20150148359A1 SELECTIVE INHIBITORS OF UNDIFFERENTIATED CELLS 公开/授权日：2015-05-28