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公开(公告)号:US09456998B2
公开(公告)日:2016-10-04
申请号:US14402467
申请日:2013-05-22
申请人: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. , Hoffmann-La Roche Inc.
IPC分类号: A61K31/4409 , A61K31/15 , A61K31/34 , A61K31/403 , A61K31/407 , A61K31/4453 , A61K31/4545 , A61K31/4985 , A61K31/136 , A61K31/155 , A61K31/165 , A61K31/166 , A61K31/341 , A61K31/343 , A61K31/381 , A61K31/4015 , A61K31/404 , A61K31/451 , A61K31/513 , G01N33/50
CPC分类号: A61K31/15 , A61K31/136 , A61K31/155 , A61K31/165 , A61K31/166 , A61K31/34 , A61K31/341 , A61K31/343 , A61K31/381 , A61K31/4015 , A61K31/403 , A61K31/404 , A61K31/407 , A61K31/4409 , A61K31/4453 , A61K31/451 , A61K31/4545 , A61K31/4985 , A61K31/513 , G01N33/502 , G01N33/5073 , G01N2500/02 , G01N2500/10
摘要: Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.
摘要翻译: 式I-VI中任何一种化合物作为未分化细胞的细胞毒性抑制剂的用途以及包含式I-VI中任一项的化合物的药物组合物以及用于鉴定用于抑制未分化细胞的潜在候选物的方法。 进一步公开了SCD-1抑制剂作为未分化细胞的细胞毒性抑制剂的用途。
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公开(公告)号:US20150148359A1
公开(公告)日:2015-05-28
申请号:US14402467
申请日:2013-05-22
申请人: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. , Hoffmann-La Roche Inc.
IPC分类号: A61K31/15 , A61K31/513 , A61K31/136 , A61K31/451 , A61K31/381 , A61K31/404 , A61K31/343 , A61K31/4015 , A61K31/407 , A61K31/166 , A61K31/341 , A61K31/155 , A61K31/165 , G01N33/50 , A61K31/4409
CPC分类号: A61K31/15 , A61K31/136 , A61K31/155 , A61K31/165 , A61K31/166 , A61K31/34 , A61K31/341 , A61K31/343 , A61K31/381 , A61K31/4015 , A61K31/403 , A61K31/404 , A61K31/407 , A61K31/4409 , A61K31/4453 , A61K31/451 , A61K31/4545 , A61K31/4985 , A61K31/513 , G01N33/502 , G01N33/5073 , G01N2500/02 , G01N2500/10
摘要: Uses of a compound of any of Formulas I-VI as a cytotoxic inhibitor of undifferentiated cells are disclosed herein, as well as pharmaceutical compositions comprising a compound of any of Formulas I-VI, and methods for identifying a lead candidate for inhibiting undifferentiated cells. Further disclosed are uses of an SCD-1 inhibitor as a cytotoxic inhibitor of undifferentiated cells.
摘要翻译: 式I-VI中任何一种化合物作为未分化细胞的细胞毒性抑制剂的用途以及包含式I-VI中任一项的化合物的药物组合物以及用于鉴定用于抑制未分化细胞的潜在候选物的方法。 进一步公开了SCD-1抑制剂作为未分化细胞的细胞毒性抑制剂的用途。
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