An internally powered sliding panel has a power source and drive train contained internally within the stiles and rails of a frame. A driven wheel is rotatably mounted on the frame and connected to the power source via the drive train. The panel may further include a lift system including a second power source, a lift mechanism, and a lift drive which are contained internally within the stiles and rails of the frame. The power sources, drive train, lift mechanism, and lift drive may be contained completely inside the stiles and rails of the frame. The movement of the panel along a fixed path, and the raising and lowering of the panel, may be regulated by a control system. The control system includes a microcontroller and sensor used to determine the position of the panel.