Invention Grant
- Patent Title: Inhibitor compounds of phosphodiesterase type 10A
- Patent Title (中): 磷酸二酯酶10A型抑制剂化合物
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Application No.: US13968242Application Date: 2013-08-15
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Publication No.: US09464085B2Publication Date: 2016-10-11
- Inventor: Hervé Geneste , Michael Ochse , Karla Drescher , Clarissa Jakob
- Applicant: AbbVie Deutschland GmbH & Co. KG , AbbVie Inc.
- Applicant Address: DE Wiesbaden US IL North Chicago
- Assignee: AbbVie Deutschland GmbH & Co. KG,AbbVie Inc.
- Current Assignee: AbbVie Deutschland GmbH & Co. KG,AbbVie Inc.
- Current Assignee Address: DE Wiesbaden US IL North Chicago
- Agency: Michael Best & Friedrich LLP
- Agent Lisa V. Mueller
- Main IPC: C07D471/14
- IPC: C07D471/14 ; C07D487/04 ; C07D471/04

Abstract:
The present invention relates to compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof. where in formula I the variables R1, R2, R3, R4 and R5 are as defined in the claims and where X is C—R6 or N, Y is C—R7 or N, where R6 and R7 are, inter alia, hydrogen, halogen, alkoxy, haloalkoxy and the like. The compounds of the formula I, the N-oxides, tautomers, the prodrugs and the pharmaceutically acceptable salts thereof are inhibitors of phosphodiesterase type 10A and to their use for the manufacture of a medicament and which thus are suitable for treating or controlling of medical disorders selected from neurological disorders and psychiatric disorders, for ameliorating the symptoms associated with such disorders and for reducing the risk of such disorders.
Public/Granted literature
- US20140051695A1 NOVEL INHIBITOR COMPOUNDS OF PHOSPHODIESTERASE TYPE 10A Public/Granted day:2014-02-20
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