A method and a system are provided for speculative periodic synchronization. A phase value representing a measured phase of the second clock signal relative to the first clock signal measured at least one cycle earlier is received. A period value representing a period of the second clock signal relative to the first clock signal measured at least one cycle earlier is also received. A reduced timing margin is determined based on the phase value and the period value. A speculatively synchronized output signal is generated based on the reduced timing margin.