发明授权
- 专利标题: RNA-interference by single-stranded RNA molecules
- 专利标题(中): 单链RNA分子的RNA干扰
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申请号: US14337710申请日: 2014-07-22
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公开(公告)号: US09476044B2公开(公告)日: 2016-10-25
- 发明人: Thomas Tuschl , Javier Martinez , Agnieszka Patkaniowska , Henning Urlaub , Reinhard Luehrmann
- 申请人: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
- 申请人地址: DE Munich
- 专利权人: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
- 当前专利权人: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.V.
- 当前专利权人地址: DE Munich
- 代理机构: Rothwell, Figg, Ernst & Manbeck, P.C.
- 优先权: EP02015532 20020710; EP02018906 20020823
- 主分类号: C12N15/11
- IPC分类号: C12N15/11 ; C07H21/04 ; C12N15/113 ; A61K47/48 ; C07K14/47 ; C07K19/00
摘要:
The present invention relates to sequence and structural features of single-stranded (ss)RNA molecules required to mediate target-specific nucleic acid modifications by RNA-interference (RNAi), such as target mRNA degradation and/or DNA methylation.
公开/授权文献
- US20150096064A1 RNA-INTERFERENCE BY SINGLE-STRANDED RNA MOLECULES 公开/授权日:2015-04-02
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