发明授权
US09476819B2 Hydrodynamic particle separation and detection systems and methods
有权
流体动力学粒子分离与检测系统及方法
- 专利标题: Hydrodynamic particle separation and detection systems and methods
- 专利标题(中): 流体动力学粒子分离与检测系统及方法
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申请号: US13822986申请日: 2011-10-19
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公开(公告)号: US09476819B2公开(公告)日: 2016-10-25
- 发明人: Tza-Huei Jeff Wang , Kelvin Jeng-Fang Liu
- 申请人: Tza-Huei Jeff Wang , Kelvin Jeng-Fang Liu
- 申请人地址: US MD Baltimore
- 专利权人: The Johns Hopkins University
- 当前专利权人: The Johns Hopkins University
- 当前专利权人地址: US MD Baltimore
- 代理机构: Venable LLP
- 代理商 Henry J. Daley
- 国际申请: PCT/US2011/056941 WO 20111019
- 国际公布: WO2012/054641 WO 20120426
- 主分类号: G01N15/14
- IPC分类号: G01N15/14 ; C12Q1/68 ; G01N21/64 ; G01N33/48 ; G01N15/02
摘要:
A method of separating, detecting and determining a size of each of a plurality of particles in a fluid includes compelling the fluid to flow through a fluid channel such that larger particles of the plurality of particles travel through the fluid channel faster than smaller particles of the plurality of particles; illuminating a detection zone of the fluid channel substantially uniformly across an entire cross section of the fluid channel such that each of the plurality of particles passes through illumination light upon passing through the detection zone; detecting each of the plurality of particles based on corresponding responses to the illuminating to determine a time that each of the plurality of particles passes through the detection zone; and determining a size of each of the plurality of particles based on the time that each of the plurality of particles passes through the detection zone.
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