发明授权
- 专利标题： Lipid microparticle growth factor formulations
- 专利标题（中）： 脂质微粒生长因子制剂
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申请号： US12446884申请日： 2007-10-23
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公开(公告)号： US09480649B2公开(公告)日： 2016-11-01
- 发明人: Leah R. Hansom , William H. Frey, II , John D. Hoekman , Jens Pohl
- 申请人： Leah R. Hansom , William H. Frey, II , John D. Hoekman , Jens Pohl
- 申请人地址： DE Heidelberg US MN Minneapolis
- 专利权人： Biopharm Gesellschaft zur biotechnologischen Entwicklung von Pharmaka mbH,HealthPartners Research Foundation
- 当前专利权人： Biopharm Gesellschaft zur biotechnologischen Entwicklung von Pharmaka mbH,HealthPartners Research Foundation
- 当前专利权人地址： DE Heidelberg US MN Minneapolis
- 代理机构： Rothwell, Figg, Ernst & Manbeck, P.C.
- 优先权： EP06022159 20061023
- 国际申请： PCT/EP2007/009198 WO 20071023
- 国际公布： WO2008/049588 WO 20080502
- 主分类号： A61K9/107
- IPC分类号： A61K9/107 ; A61K38/47 ; A61K9/00 ; A61K38/18
摘要：
The present invention is directed to novel formulations and methods for the improved delivery and administration of hydrophobic therapeutic compounds that are substantially insoluble and/or susceptible to precipitation in aqueous solution at physiological pH, including, e.g., growth and differentiation factor-5 and related proteins. Many therapeutic compounds are hydrophobic at physiological pH levels.
公开/授权文献
- US20100074959A1 LIPID GROWTH FACTOR FORMULATIONS 公开/授权日：2010-03-25
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