Crosstalk can be suppressed in photonic switching fabrics by activating unused photonic elements in a manner that manipulates the inactive connections and inhibits the propagation of cross-talk over the switching fabric. For example, unused photonic elements can be set to a cross or bar configuration to block first and second order crosstalk from propagating to the output ports, thereby reducing noise in the output signals. All of the unused elements can be activated in order to maximize crosstalk suppression. Alternatively, fewer than all of the unused elements may be activated to achieve a balance between crosstalk suppression and power conservation. Photonic switch architectures can be configured to use pre-determined cross-talk suppression maps (e.g., patterns of activated unused cells) for the various switching configurations, which may be computed using a recursive algorithm.