发明授权
- 专利标题： Two-component tissue adhesive and method for producing same
- 专利标题（中）： 双组分组织粘合剂及其制备方法
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申请号： US13877880申请日： 2011-10-04
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公开(公告)号： US09499728B2公开(公告)日： 2016-11-22
- 发明人: Tetsushi Taguchi , Miyuki Matsuda
- 申请人： Tetsushi Taguchi , Miyuki Matsuda
- 申请人地址： JP Ibaraki
- 专利权人： National Institute for Materials Science
- 当前专利权人： National Institute for Materials Science
- 当前专利权人地址： JP Ibaraki
- 代理机构： Hoffman & Baron, LLP
- 优先权： JP2010-225368 20101005
- 国际申请： PCT/JP2011/072835 WO 20111004
- 国际公布： WO2012/046717 WO 20120412
- 主分类号： C09J189/00
- IPC分类号： C09J189/00 ; C09H7/00 ; A61L24/10 ; A61K38/00
摘要：
The present invention addresses the problem of providing: a two-component tissue adhesive having high adhesive strength and high biocompatibility; and a method for producing the two-component tissue adhesive. The present invention involves a two-component tissue adhesive comprising hydrophobically-modified gelatin as a first agent and a cross-linking reagent as a second agent. The hydrophobically-modified gelatin is provided with an amino group and a hydrophobic group on the side chain thereof, and the cross-linking reagent has two or more active ester groups or anhydrides within a single molecule.
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