发明授权
US09499827B2 Compositions and methods comprising sequences having meganuclease activity
有权
包含具有大范围核酸酶活性的序列的组合物和方法
- 专利标题： Compositions and methods comprising sequences having meganuclease activity
- 专利标题（中）： 包含具有大范围核酸酶活性的序列的组合物和方法
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申请号： US13886317申请日： 2013-05-03
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公开(公告)号： US09499827B2公开(公告)日： 2016-11-22
- 发明人: Ericka Bermudez , Andrew Mark Cigan , James English , Saverio Carl Falco , Huirong Gao , Lu Liu , Zhan-Bin Liu , Azalea Ong , Sergei Svitashev , Joshua K Young
- 申请人： E I DU PONT DE NEMOURS AND COMPANY , PIONEER HI BRED INTERNATIONAL INC
- 申请人地址： US DE Wilmington US IA Johnston
- 专利权人： E I DU PONT DE NEMOURS AND COMPANY,PIONEER HI-BRED INTERNATIONAL, INC.
- 当前专利权人： E I DU PONT DE NEMOURS AND COMPANY,PIONEER HI-BRED INTERNATIONAL, INC.
- 当前专利权人地址： US DE Wilmington US IA Johnston
- 主分类号： C12N15/82
- IPC分类号： C12N15/82 ; C12N5/14 ; C12N9/22 ; C12N9/16 ; C12N15/81
摘要：
Compositions and methods comprising polynucleotides and polypeptides having meganuclease activity are provided. Further provided are nucleic acid constructs, yeast, plants, plant cells, explants, seeds and grain having the meganuclease sequences. Various methods of employing the meganuclease sequences are provided. Such methods include, for example, methods for producing a meganuclease with increased activity at a wide range of temperatures, methods for producing a yeast, plant, plant cell, explant or seed comprising a meganuclease with increased activity.
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