发明授权
- 专利标题： Lipids and lipid compositions for the delivery of active agents
- 专利标题（中）： 用于递送活性剂的脂质和脂质组合物
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申请号： US14200359申请日： 2014-03-07
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公开(公告)号： US09504747B2公开(公告)日： 2016-11-29
- 发明人: Jeremy Lee Baryza , Rohan Eric John Beckwith , Keith Bowman , Crystal Byers , Tanzina Fazal , Gabriel Grant Gamber , Cameron Chuck-munn Lee , Ritesh Bhanudasji Tichkule , Chandra Vargeese , Shuangxi Wang , Laura Ellen West , Thomas Zabawa , Junping Zhao
- 申请人： Jeremy Lee Baryza , Rohan Eric John Beckwith , Keith Bowman , Crystal Byers , Tanzina Fazal , Gabriel Grant Gamber , Cameron Chuck-munn Lee , Ritesh Bhanudasji Tichkule , Chandra Vargeese , Shuangxi Wang , Laura Ellen West , Thomas Zabawa , Junping Zhao
- 申请人地址： CH Basel
- 专利权人： Novartis AG
- 当前专利权人： Novartis AG
- 当前专利权人地址： CH Basel
- 代理机构： Brinks Gilson & Lione
- 主分类号： A61K47/18
- IPC分类号： A61K47/18 ; C07C229/12 ; A61K47/22 ; A61K9/127 ; C07C217/58 ; C07C217/60 ; C07C217/62 ; C07C219/22 ; C07C219/28 ; C07C235/46 ; C07C237/08 ; C07D213/79 ; C07D317/24 ; C07D317/28 ; C07D205/04 ; C07D295/096 ; C07D213/69 ; C12N15/113
摘要：
This invention provides for a compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein R1-R4, L and X are defined herein. The compounds of formula (I) and pharmaceutically acceptable salts thereof are cationic lipids useful in the delivery of biologically active agents to cells and tissues.
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