发明授权
- 专利标题： Methods and compositions for the selection and optimization of oligonucleotide tag sequences
- 专利标题（中）： 用于选择和优化寡核苷酸标签序列的方法和组合物
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申请号： US14004107申请日： 2012-03-12
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公开(公告)号： US09512467B2公开(公告)日： 2016-12-06
- 发明人: Norman C. Nelson , Jijumon Chelliserry
- 申请人： Norman C. Nelson , Jijumon Chelliserry
- 申请人地址： US CA San Diego
- 专利权人： GEN-PROBE INCORPORATED
- 当前专利权人： GEN-PROBE INCORPORATED
- 当前专利权人地址： US CA San Diego
- 代理商 Jeffrey E. Landes
- 国际申请： PCT/US2012/028797 WO 20120312
- 国际公布： WO2012/122571 WO 20120913
- 主分类号： C12Q1/68
- IPC分类号： C12Q1/68 ; G06F19/20 ; C12N15/10
摘要：
Methods for selecting tag-oligonucleotide sequences for use in an in vitro nucleic acid assay. The selected tag sequences are useful for nucleic acid assay wherein interference between the nucleic acid sequences is the assay is to be controlled. Selected tag sequences are incorporated into nucleic acid assay to improve the performance of and/or minimize any interference between nucleic acids in the assay compared to untagged assays.
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