Invention Grant
US09518295B2 High-throughput sequencing method for methylated DNA and use thereof
有权
甲基化DNA的高通量测序方法及其用途
- Patent Title: High-throughput sequencing method for methylated DNA and use thereof
- Patent Title (中): 甲基化DNA的高通量测序方法及其用途
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Application No.: US13814925Application Date: 2010-08-11
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Publication No.: US09518295B2Publication Date: 2016-12-13
- Inventor: Yan Wang , Mingzhi Ye , Xu Han , Xiuqing Zhang , Zhongsheng Sun
- Applicant: Yan Wang , Mingzhi Ye , Xu Han , Xiuqing Zhang , Zhongsheng Sun
- Applicant Address: CN Beijing CN Shenzhen, Guangdong
- Assignee: Institute of Psychology, Chinese Academy of Sciences,BGI Shenzhen Co., Ltd.
- Current Assignee: Institute of Psychology, Chinese Academy of Sciences,BGI Shenzhen Co., Ltd.
- Current Assignee Address: CN Beijing CN Shenzhen, Guangdong
- Agency: Wilmer Cutler Pickering Hale and Dorr LLP
- International Application: PCT/CN2010/001219 WO 20100811
- International Announcement: WO2012/019320 WO 20120216
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12N15/10
Abstract:
The present invention provides a high-throughput sequencing method for methylated DNA, and use thereof. Particularly, the present invention provides a high-throughput sequencing method for methylated DNA, which combines methylated DNA immunoprecipitation, removal of repetitive sequences, and bisulfite treatment. The site of sequencing library will be decreased, and the cost will be reduced by using the method disclosed in the present invention.
Public/Granted literature
- US20130244885A1 HIGH-THROUGHPUT SEQUENCING METHOD FOR METHYLATED DNA AND USE THEREOF Public/Granted day:2013-09-19
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