公开(公告)号：US20210144990A1

公开(公告)日：2021-05-20

申请号：US17045153

申请日：2019-04-05

Applicant: Xu HAN ,  Henry W. WHITE ,  Peter KOULEN

Inventor： Xu HAN ,  Henry W. WHITE ,  Peter KOULEN

IPC: A01N1/02 ,  F25D29/00 ,  G01N1/42

Abstract: An improved ultra-fast cooling system is disclosed for cryopreservation of biomaterials. The ultra-fast cooling system is designed to uniformly vitrify or partially vitrify biomaterials, including but not limited to, human biomaterials, proteins, peptides, cells, stem cells, antibodies, neurons, human tissue, organs, cornea, skin, retina, eggs, sperm, embryos, body fluids, blood, serum, lymph fluid, animal tissue, plant biomaterials, plant tissue, germ plasma, pollen, plant sap, and bioengineered tissue, without cryoprotectants or with a low concentration of cryoprotectants. Cooling rates are sufficient to uniformly cryopreserve biomaterials, and can be used in diagnostic cytology and biological cryofixation applications. Other materials also can be cooled uniformly, such as inorganic materials for processing.

公开(公告)号：US09322632B2

公开(公告)日：2016-04-26

申请号：US13601305

申请日：2012-08-31

Applicant: Xinyu Zhou ,  Moussa Ndiaye ,  Michael Partridge ,  Xu Han ,  Michael McLeod

Inventor： Xinyu Zhou ,  Moussa Ndiaye ,  Michael Partridge ,  Xu Han ,  Michael McLeod

IPC: G01B7/14 ,  G01B7/00 ,  G01D5/20 ,  G01D1/00 ,  G01B1/00

CPC classification number: G01B7/003 ,  G01B1/00 ,  G01B2290/00 ,  G01D1/00 ,  G01D5/2033

Abstract: A linear position sensor assembly having a magnetic shield minimizes interference (noise) from adjacent electrical and electromagnetic devices, particularly solenoids. The sensor assembly includes a permanent magnet linear contactless displacement (PLCD) sensor comprising a pair of magnetic field sensors which are spaced apart by a member of high magnetic permeability such as a metal bar. The sensors and metal bar are enclosed, i.e., surrounded on three sides, by a cover or shield of high magnetic permeability material such as steel or mu metal, for example. A permanent magnet is disposed in sensed proximity to the sensors and translates with a clutch actuator component. When the clutch actuator component translates axially, the two field sensors provide a signal to associated electronics having high linearity, low noise and no deadband.

Abstract translation: 具有磁屏蔽的线性位置传感器组件最小化来自相邻电气和电磁装置（特别是螺线管）的干扰（噪声）。 传感器组件包括永磁体线性非接触位移（PLCD）传感器，其包括由诸如金属棒的高磁导率构件隔开的一对磁场传感器。 传感器和金属棒被封闭，即三面包围，例如由诸如钢或者金属的高导磁率材料的盖子或屏蔽件。 永磁体设置在传感器附近，并与离合器致动器部件平移。 当离合器致动器部件轴向平移时，两个场传感器向具有高线性度，低噪声和无死区的相关电子器件提供信号。

公开(公告)号：US20150072424A1

公开(公告)日：2015-03-12

申请号：US14482692

申请日：2014-09-10

Applicant: HONGBIN MA ,  Fengmin Su ,  Xu Han ,  Hsiu-Hung Chen

Inventor： HONGBIN MA ,  Fengmin Su ,  Xu Han ,  Hsiu-Hung Chen

IPC: F25D7/00 ,  A01N1/02

CPC classification number: F25D3/10 ,  A01N1/0252 ,  F28F13/187

Abstract: One aspect of the present invention is directed to an apparatus for cryogenically cooling a substance. The apparatus of the present invention includes a thin film evaporator comprising a microstructured surface and an applicator for dispensing a working fluid onto the microstructured surface. The apparatus preferably contains a pressure-controlled vessel enclosing the thin film evaporator and at least a portion of the applicator. In a second aspect, the present invention is directed to the method of using a thin film evaporator of the present invention to cryogenically cool a substance by forming a thin film layer of the working fluid on the microstructured surface of the thin film evaporator.

Abstract translation: 本发明的一个方面涉及用于低温冷却物质的装置。 本发明的装置包括薄膜蒸发器，其包括微结构化表面和用于将工作流体分配到微结构化表面上的施加器。 该装置优选地包含包围薄膜蒸发器的压力控制容器和至少一部分施加器。 在第二方面，本发明涉及使用本发明的薄膜蒸发器的方法，通过在薄膜蒸发器的微结构化表面上形成工作流体的薄膜层来低温冷却物质。

公开(公告)号：US08487494B2

公开(公告)日：2013-07-16

申请号：US13238008

申请日：2011-09-21

Applicant: Sinisa Jurkovic ,  Khwaja M. Rahman ,  Xinyu Zhou ,  Xu Han ,  Qiang Niu

Inventor： Sinisa Jurkovic ,  Khwaja M. Rahman ,  Xinyu Zhou ,  Xu Han ,  Qiang Niu

IPC: H02K1/27

CPC classification number: H02K1/2766 ,  H02K1/276

Abstract: An interior permanent magnet machine is provided with a rotor that includes a plurality of slots and at least one barrier defined by the plurality of slots. A plurality of first and second magnets are disposed within the barrier. The rotor is configured such that at least one of the first magnets is located at a different radial distance from the center of the rotor relative to at least one of the second magnets. The rotor may be configured to produce an averaging effect similar to that achieved through traditional skewing of rotor magnets. The rotor includes a plurality of poles defined by respective pole axes in the rotor and may be configured to reflect radial asymmetry between poles (pole-to-pole) and/or radial asymmetry within a pole.

Abstract translation: 内置永磁电机设有转子，转子包括多个槽和由多个槽限定的至少一个挡板。 多个第一和第二磁体设置在屏障内。 转子被构造成使得至少一个第一磁体位于与转子的中心相对于至少一个第二磁体不同的径向距离处。 转子可以被配置成产生类似于通过转子磁体的传统偏斜实现的平均效果。 转子包括由转子中的相应极轴限定的多个极，并且可以被配置成反射极之间的极（极 - 极）和/或径向不对称之间的径向不对称。

公开(公告)号：US20130141082A1

公开(公告)日：2013-06-06

申请号：US13601305

申请日：2012-08-31

Applicant: Xinyu Zhou ,  Moussa Ndiaye ,  Michael Partridge ,  Xu Han ,  Michael Mcleod

Inventor： Xinyu Zhou ,  Moussa Ndiaye ,  Michael Partridge ,  Xu Han ,  Michael Mcleod

IPC: G01B7/14

CPC classification number: G01B7/003 ,  G01B1/00 ,  G01B2290/00 ,  G01D1/00 ,  G01D5/2033

Abstract: A linear position sensor assembly having a magnetic shield minimizes interference (noise) from adjacent electrical and electromagnetic devices, particularly solenoids. The sensor assembly includes a permanent magnet linear contactless displacement (PLCD) sensor comprising a pair of magnetic field sensors which are spaced apart by a member of high magnetic permeability such as a metal bar. The sensors and metal bar are enclosed, i.e., surrounded on three sides, by a cover or shield of high magnetic permeability material such as steel or mu metal, for example. A permanent magnet is disposed in sensed proximity to the sensors and translates with a clutch actuator component. When the clutch actuator component translates axially, the two field sensors provide a signal to associated electronics having high linearity, low noise and no deadband.

Abstract translation: 具有磁屏蔽的线性位置传感器组件最小化来自相邻电气和电磁装置（特别是螺线管）的干扰（噪声）。 传感器组件包括永磁体线性非接触位移（PLCD）传感器，其包括由诸如金属棒的高磁导率构件隔开的一对磁场传感器。 传感器和金属棒被封闭，即三面包围，例如由诸如钢或者金属的高导磁率材料的盖子或屏蔽件。 永磁体设置在传感器附近，并与离合器致动器部件平移。 当离合器致动器部件轴向平移时，两个场传感器向具有高线性度，低噪声和无死区的相关电子器件提供信号。

公开(公告)号：US20110271267A1

公开(公告)日：2011-11-03

申请号：US12769763

申请日：2010-04-29

Applicant: Franck EXCOFFIER ,  Michael P. GROOVER ,  Xu HAN ,  Andreas B.M. KOSTER ,  Edward H. LIN ,  Mario SWEENEY

Inventor： Franck EXCOFFIER ,  Michael P. GROOVER ,  Xu HAN ,  Andreas B.M. KOSTER ,  Edward H. LIN ,  Mario SWEENEY

IPC: G06F9/445 ,  G06F9/44

CPC classification number: G06F8/65

Abstract: Various embodiments for updating at least one facility in a computing storage environment are provided. In one embodiment, a sequence for distributing at least one of a plurality of code packages to the at least one facility according to different states of a fixed state machine is set. The at least one of the plurality of code packages is installed in at least one staging area. The at least one of the plurality of code packages is maintained in the at least one staging area in a valid, dormant mode while the fixed state machine is stopped. Pursuant to a resumption of the fixed state machine at a subsequent time, a current code package is swapped with the at least one of the plurality of code packages in the at least one staging area to activate the at least one of the plurality of code packages.

Abstract translation: 提供了用于在计算存储环境中更新至少一个设施的各种实施例。 在一个实施例中，设置用于根据固定状态机的不同状态将多个代码包中的至少一个分配给至少一个设施的序列。 所述多个代码包中的至少一个被安装在至少一个分段区域中。 在固定状态机停止时，多个代码包中的至少一个被保持在有效的休眠模式的至少一个暂存区域中。 根据随后的时间恢复固定状态机，当前代码包与至少一个暂存区域中的多个代码包中的至少一个交换，以激活多个代码包中的至少一个代码包 。

公开(公告)号：US20110271100A1

公开(公告)日：2011-11-03

申请号：US12769790

申请日：2010-04-29

Applicant: Franck EXCOFFIER ,  Michael P. GROOVER ,  Xu HAN ,  Andreas B.M. KOSTER ,  Edward H. LIN ,  Mario SWEENEY

Inventor： Franck EXCOFFIER ,  Michael P. GROOVER ,  Xu HAN ,  Andreas B.M. KOSTER ,  Edward H. LIN ,  Mario SWEENEY

IPC: H04L29/06

CPC classification number: H04L9/3263 ,  G06F21/572

Abstract: Various embodiments for providing an update to at least one storage facility in a computing storage environment are provided. In one embodiment, a security verification is performed on the update via a certificate authentication mechanism to confirm a validity of the update. Subsequent to confirming the validity of the update, a safety verification on the update is performed to confirm a suitability of the update to the at least one storage facility. If the security and safety verifications are validated, the update is provided and installed in the at least one storage facility.

Abstract translation: 提供了用于向计算存储环境中的至少一个存储设施提供更新的各种实施例。 在一个实施例中，通过证书认证机制对更新执行安全验证，以确认更新的有效性。 在确认更新的有效性之后，执行更新的安全验证，以确认对至少一个存储设施的更新的适用性。 如果安全和安全验证被验证，则提供更新并将其安装在至少一个存储设施中。

公开(公告)号：US20090271138A1

公开(公告)日：2009-10-29

申请号：US12111461

申请日：2008-04-29

Applicant: UDAY P. KORDE ,  POCHUAN B. HSING ,  XU HAN ,  XINYU ZHOU ,  ROHIT S. PARANJPE ,  JOSEPH P. KELLY ,  JULIAN J. BLAIR ,  DONALD R. JONES

Inventor： UDAY P. KORDE ,  POCHUAN B. HSING ,  XU HAN ,  XINYU ZHOU ,  ROHIT S. PARANJPE ,  JOSEPH P. KELLY ,  JULIAN J. BLAIR ,  DONALD R. JONES

IPC: G06F19/00 ,  G01M19/00

CPC classification number: G01M13/02

Abstract: A method for calibrating a physical test cell includes the steps of: determining a set of inputs to be provided to the physical test cell based in part on a set of historical test data; providing the inputs to the physical test cell and receiving a set of outputs associated therewith, wherein the providing includes implementing a sequential space filling sampling procedure to substantially cover a region defined by the set of historical values; creating a virtual test cell comprising one or more response surfaces based on the set of outputs; and interrogating the virtual test cell to determine a calibration relationship between at least one of the inputs and at least one of the outputs. Smooth Kriging may be used to determine the virtual test cell.

Abstract translation: 用于校准物理测试单元的方法包括以下步骤：部分地基于一组历史测试数据确定要提供给物理测试单元的一组输入; 向所述物理测试单元提供输入并接收与其相关联的一组输出，其中所述提供包括实现顺序空间填充抽样程序以基本上覆盖由所述一组历史值定义的区域; 基于所述一组输出创建包括一个或多个响应面的虚拟测试单元; 以及询问所述虚拟测试单元以确定所述输入中的至少一个与所述输出中的至少一个之间的校准关系。 可以使用平滑克里金法来确定虚拟测试单元。

公开(公告)号：US20190313632A1

公开(公告)日：2019-10-17

申请号：US16300970

申请日：2017-05-15

Applicant: XU HAN ,  YE YUAN ,  ROBERT MICHAEL ROBERTS

Inventor： XU HAN ,  YE YUAN ,  ROBERT MICHAEL ROBERTS

IPC: A01N1/02 ,  C12N1/04

Abstract: The present invention is directed to a medium for preserving cells at non-cryogenic freezing temperatures. The medium comprises a hydrophilic and nontoxic polymer or other macromolecule, an aqueous liquid, and a cryoprotectant. The molecules of the macromolecule form compact three-dimensional structures that are spherical in shape when dissolved in the aqueous liquid. The medium of the present invention can be used for long-term storage of cells at non-cryogenic temperatures with outcomes similar to those seen with storage at cryogenic temperatures.

公开(公告)号：US08884485B2

公开(公告)日：2014-11-11

申请号：US13448508

申请日：2012-04-17

Applicant: Sinisa Jurkovic ,  Khwaja M. Rahman ,  Xinyu Zhou ,  Xu Han ,  Qiang Niu

Inventor： Sinisa Jurkovic ,  Khwaja M. Rahman ,  Xinyu Zhou ,  Xu Han ,  Qiang Niu

IPC: H02K21/12

CPC classification number: H02K1/2766 ,  H02K16/02 ,  H02K29/03 ,  H02K2201/03 ,  H02K2213/03

Abstract: A permanent magnet machine is provided with a rotor positioned at least partially within a stator. The rotor includes first and second ring segments oriented axially around a central axis. The rotor defines first and second configurations in the first and second ring segments, respectively. The first configuration is sufficiently different from the second configuration such that torque ripple may be minimized. A first layer of slots, defining a slot outer edge, may be formed in the rotor. In one embodiment, a stator-to-slot gap varies between the first and second ring segments. In another embodiment, a stator-rotor gap varies between the first and second ring segments. In another embodiment, a bridge thickness varies between the first and second ring segments. Thus the rotor exhibits axial asymmetry.

Abstract translation: 一种永磁体机器设置有至少部分位于定子内的转子。 转子包括围绕中心轴线轴向取向的第一和第二环形段。 转子分别限定第一和第二环段中的第一和第二构造。 第一配置与第二配置充分不同，使得扭矩波动可能被最小化。 限定槽外边缘的第一层槽可以形成在转子中。 在一个实施例中，定子与槽间隙在第一和第二环段之间变化。 在另一个实施例中，定子 - 转子间隙在第一和第二环段之间变化。 在另一个实施例中，桥接厚度在第一和第二环段之间变化。 因此转子表现出轴向不对称性。