Technical effects of a method, an apparatus, and a system for operating a shared resource in an asynchronous multiprocessing system that are provided in the present invention are as follows: A processor in an asynchronous multiprocessing system implements an operation on a shared resource by locking a hardware resource lock, and the hardware resource lock is implemented by a register; in this way, a bus in the asynchronous multiprocessing system does not need to support a synchronization operation, and the processor also does not need to have a feature of supporting a synchronization operation, and is capable of implementing the operation on the shared resource only in a manner of accessing the register, which simplifies the operation on the shared resource by the processor in the asynchronous multiprocessing system, enlarges a selection range of the processor in the asynchronous multiprocessing system, and further improves flexibility of the asynchronous multiprocessing system.