发明授权
- 专利标题: Process for the enzymatic production of carnitine from beta-lactones
- 专利标题(中): 从β-内酯酶促生产肉碱的方法
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申请号: US13557922申请日: 2012-07-25
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公开(公告)号: US09523106B2公开(公告)日: 2016-12-20
- 发明人: Ellen Klegraf , Manuela Avi
- 申请人: Ellen Klegraf , Manuela Avi
- 申请人地址: CH Visp
- 专利权人: LONZA LTD.
- 当前专利权人: LONZA LTD.
- 当前专利权人地址: CH Visp
- 代理机构: Hoffmann & Baron, LLP
- 优先权: EP11006163 20110727
- 主分类号: C12P13/00
- IPC分类号: C12P13/00 ; C12P7/42 ; C12P7/62 ; C12P41/00
摘要:
Subject of the invention is a process for the production of L-carnitine, wherein a β-lactone, which is a 4-(halomethyl)oxetane-2-one, is converted into L-carnitine, wherein the process comprises an enzymatic conversion of the β-lactone into (R)-4-halo-3-hydroxybutyric acid or (R)-4-halo-3-hydroxybutyric acid ester.
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