公开(公告)号：US20230048275A1

公开(公告)日：2023-02-16

申请号：US17786566

申请日：2020-12-18

申请人： CARBIOS

发明人： ALAIN MARTY ,  MICHEL CHATEAU ,  MADIHA ALOUI DALIBEY

IPC分类号： C08J11/10 ,  C08J9/08 ,  C08J9/12 ,  C12P7/62

摘要： The present invention relates to a process for degrading a plastic product comprising at least one polymer, said process comprising the steps of foaming at least partially the plastic product; and depolymerizing at least one target polymer of the at least partially foamed plastic product, wherein the step of foaming is performed at a temperature at which the plastic product is in a partially or totally molten state.

公开(公告)号：US20230033620A1

公开(公告)日：2023-02-02

申请号：US17757711

申请日：2020-12-17

申请人： Evonik Operations GmbH

发明人： Stefan Julian Liebig ,  Jan Marian von Hof ,  Thomas Böhmer ,  Thomas Thomalla ,  Kathrin Daniela Brandt ,  Christian Hartung ,  Hans Henning Wenk ,  Maxim Yavorsky ,  Sunay Karacocuk

IPC分类号： C12P7/6454 ,  C12P7/62

摘要： Xylitol carboxylates are products of interest in the food and cosmetics industries. A process can be used for the enzymatic preparation of xylitol carboxylates.

公开(公告)号：US11566268B2

公开(公告)日：2023-01-31

申请号：US14213713

申请日：2014-03-14

申请人： ISIS INNOVATION LTD ,  GOVERNMENT OF THE USA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES

发明人： Kieran Clarke ,  Richard Lewis Veech ,  M. Todd King

IPC分类号： C12P7/62 ,  C07C67/03 ,  C07C29/147

摘要： Embodiments of the present invention are directed to processes for the production of (R)-3-hydroxybutyl (R)-3-hydroxybyrate. Poly (R)-3-hydroxybyrate is transesterified with an alcohol, to form a first ester portion and a second ester portion. The first ester portion is reduced to the diol to form a diol portion and the diol portion is reacted with the second ester portion to produce (R)-3-hydroxybutyl (R)-3-hydroxybyrate.

公开(公告)号：US11549129B2

公开(公告)日：2023-01-10

申请号：US16230660

申请日：2018-12-21

申请人： GENECIS BIOINDUSTRIES INC.

发明人： Luna Yu ,  Hasitha de Alwis Weerasekera ,  Marcos Forattini Lemos Igreja ,  Vani Sankar ,  Michael James Williamson ,  Sudhanshu Sanjay Soman ,  Kaitlyn Chow

IPC分类号： C12P7/62 ,  C12M1/00 ,  C12M1/26 ,  C12P7/625 ,  C12M1/33

摘要： According to one broad aspect of this disclosure, a method is provided for producing polyhydroxyalkanoates (PHA) from organic waste. The method comprises homogenizing organic waste to obtain a feedstock that has 1:1 to 3:1 (w/w) water to organic waste ratio. The feedstock is inoculated with an inoculum of acidogenic fermentative bacteria in order to obtain an inoculated feedstock. The inoculated feedstock is incubated for 5 to 10 days, 3 to 10 days, optionally 7 days, optionally 3 days, to obtain a fermentation broth. The fermentation broth comprises volatile fatty acids (VFAs) and undigested organic waste. The fermentation broth is filtered with a filter with a pore size ranging from 0.2 μm to 500,000 NMWC to remove the acidogenic fermentative bacteria and undigested organic waste, to obtain a clarified broth comprising concentrated VFAs. The clarified broth and high-PHA producing bacteria are incubated to produce intracellular PHA granules in the high-PHA producing bacteria. PHA polymers are extracted from the intracellular PHA granules.

公开(公告)号：US20220306999A1

公开(公告)日：2022-09-29

申请号：US17636351

申请日：2020-08-18

申请人： Ginkgo Bioworks, Inc.

发明人： Kim Cecelia Anderson ,  Dylan Alexander Carlin ,  Nicholas Flores ,  Katrina Forrest ,  Ramya L. Prathuri ,  Gabriel Rodriguez ,  Michelle Spencer

IPC分类号： C12N9/10 ,  C12P7/62 ,  C12P7/42 ,  C12N15/81

摘要： The disclosure relates to biosynthesis of cannabinoids and cannabinoid precursors in recombinant cells and in vitro comprising the use of disclosed prenyltransferase variants.

公开(公告)号：US11365432B2

公开(公告)日：2022-06-21

申请号：US16573796

申请日：2019-09-17

申请人： Genomatica, Inc.

发明人： Liang Wu ,  Axel Christoph Trefzer ,  Stefaan Marie Andre De Wildeman ,  Marco Alexander Van Den Berg

IPC分类号： C12P7/44 ,  C12P7/62 ,  C12P17/10 ,  C12N15/70

摘要： The present invention relates to a method for preparing an adipate ester or thioester. The invention further relates to a method for preparing adipic acid from said ester or thioester. Further the invention provides a number of methods for preparing an intermediate for said ester or thioester. Further the invention relates to a method for preparing 6-amino caproic acid (6-ACA), a method for preparing 5-formyl valeric acid (5-FVA), and a method for preparing caprolactam. Further, the invention relates to a host cell for use in a method according to the invention.

公开(公告)号：US11324217B2

公开(公告)日：2022-05-10

申请号：US16989851

申请日：2020-08-10

申请人： QINGDAO AGRICULTURAL UNIVERSITY

发明人： Fengyu Du ,  Lin Xiao

IPC分类号： A01N37/38 ,  A01N25/14 ,  A01N35/04 ,  C12P7/26 ,  C12P7/62 ,  A01N63/36

摘要： A method of isolating a compound 1 and a compound 2 includes: providing Penicillium sp. TR85; inoculating the Penicillium sp. TR85 into a sterilized solid medium; resting for fermentation at room temperature, and obtaining a fermentation product. The fermentation product includes the compound 1 and the compound 2. An herbicidal composition includes a compound 1 or a compound 2; and pesticide-acceptable adjuvants.

公开(公告)号：US11293040B2

公开(公告)日：2022-04-05

申请号：US16308890

申请日：2017-07-19

申请人： Firmenich SA

发明人： Michel Schalk ,  Letizia Rocci

IPC分类号： C12P7/62 ,  C12P5/00 ,  C12P7/22 ,  C12P7/26 ,  C12N9/02 ,  C12N9/88 ,  C12N15/70

摘要： Provided is a method of producing one or more sesquiterpene compounds comprising: contacting an acyclic FPP precursor with a polypeptide having terpene synthase activity, wherein the polypeptide comprises an amino acid sequence that has at least 55% sequence identity to SEQ ID NO: 1, to produce one or more terpenes selected from the group consisting of isovalencene, spirovetiva-1(10),7(11)-diene and valencene or derivatives thereof, or mixture of sesquiterpenes comprising one or more of isovalencene, spirovetiva-1(10),7(11)-diene and/or valencene; and optionally isolating the one or more terpenes or the mixture. Also described is a nucleic acid derived from Vetiveria zizanoides encoding a polypeptide having sesquiterpene synthase activity, a polypeptide that can be used to produce one or more sesquiterpenes or a mixture of sesquiterpenes comprising one or more of isovalencene, spirovetiva-1(10),7(11)-diene and/or valencene, and a non-human organism or cell comprising the nucleic acid or comprising an expression vector comprising the nucleic acid.

公开(公告)号：US11274321B2

公开(公告)日：2022-03-15

申请号：US15963536

申请日：2018-04-26

申请人： Kiverdi, Inc.

发明人： John S. Reed ,  Lisa Dyson

IPC分类号： C12N1/20 ,  C12P7/62 ,  C12P7/625 ,  C12M1/00 ,  C12N1/12 ,  C25B15/02 ,  C12P7/6463 ,  C25B1/04

摘要： Compositions and methods for a hybrid biological and chemical process that captures and converts carbon dioxide and/or other forms of inorganic carbon and/or CI carbon sources including but not limited to carbon monoxide, methane, methanol, formate, or formic acid, and/or mixtures containing CI chemicals including but not limited to various syngas compositions, into organic chemicals including biofuels or other valuable biomass, chemical, industrial, or pharmaceutical products are provided. The present invention, in certain embodiments, fixes inorganic carbon or CI carbon sources into longer carbon chain organic chemicals by utilizing microorganisms capable of performing the oxyhydrogen reaction and the autotrophic fixation of CO2 in one or more steps of the process.

公开(公告)号：US20220033863A1

公开(公告)日：2022-02-03

申请号：US17504858

申请日：2021-10-19

申请人： Fudan University

发明人： Fener CHEN ,  Dang CHENG ,  Zedu HUANG ,  Chen HU ,  Meifen JIANG ,  Minjie LIU ,  Huashan HUANG

IPC分类号： C12P7/62 ,  C12N11/084 ,  C12M1/40 ,  C12M3/06 ,  C12M1/00 ,  C12N11/089

摘要： Disclosed herein relates to biopharmaceuticals, and more particularly to a continuous flow method for preparing (R)-3-hydroxy-5-hexenoate. Carbonyl reductase and isopropanol dehydrogenase are co-immobilized onto an inert solid medium simultaneously to prepare a carbonyl reductase/isopropanol dehydrogenase co-immobilized catalyst, which is then filled into a microchannel reactor of the micro reaction system. A solution containing substrate 3-carbonyl-5-hexenoate is subsequently pumped into the microchannel reactor to perform an asymmetric carbonyl reduction reaction to obtain (R)-3-hydroxy-5-hexenoate.