Invention Grant
US09526771B2 Antigen composition, preparation method and use thereof, and tumor vaccine
有权
抗原组成，其制备方法及用途及肿瘤疫苗
- Patent Title: Antigen composition, preparation method and use thereof, and tumor vaccine
- Patent Title (中): 抗原组成，其制备方法及用途及肿瘤疫苗
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Application No.: US14394986Application Date: 2013-02-04
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Publication No.: US09526771B2Publication Date: 2016-12-27
- Inventor: Guangjun Nie , Xin Tian , Motao Zhu
- Applicant: National Center for Nanoscience and Technology
- Applicant Address: CN
- Assignee: NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY
- Current Assignee: NATIONAL CENTER FOR NANOSCIENCE AND TECHNOLOGY
- Current Assignee Address: CN
- Agency: Volpe & Koenig, P.C.
- Priority: CN201210113199 20120417
- International Application: PCT/CN2013/071329 WO 20130204
- International Announcement: WO2013/155890 WO 20131024
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C12N5/0784
Abstract:
The present invention provides a preparation method of an antigen composition. The preparation method comprises the following steps: (1) obtaining a tumor antigen protein; (2) making the tumor antigen protein into contact with an immature dendritic cell; (3) inducing the immature dendritic cell in contact with the tumor antigen into a mature dendritic cell; and (4) separating a cell vesicle of the mature dendritic cell. The present invention further provides an antigen composition obtained through the preparation method and the application thereof in preparing a tumor vaccine.
Public/Granted literature
- US20150093415A1 ANTIGEN COMPOSITION, PREPARATION METHOD AND USE THEREOF, AND TUMOR VACCINE Public/Granted day:2015-04-02
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