A method of multi-hop cooperative communication includes recognizing a plurality of relays capable of cooperating with one another to amplify or quantize and forward mixed signals received from a plurality of different nodes, selecting a transmission mode from a direct mode for transmission from a base station directly and a cooperation mode for transmission from the base station via the plurality of relays, transmitting data from the base station directly to a terminal through a first radio resource in the direct mode in response to the selected transmission mode being the direct mode, and transmitting data from the base station to the terminal via the plurality of relays through a second radio resource in the cooperation mode in response to the selected transmission mode being the cooperation mode.