发明授权
US09539328B2 Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
有权
防篡改组合物包含氢可酮和对乙酰氨基酚，用于快速发作和延长的止痛持续时间
- 专利标题： Tamper resistant composition comprising hydrocodone and acetaminophen for rapid onset and extended duration of analgesia
- 专利标题（中）： 防篡改组合物包含氢可酮和对乙酰氨基酚，用于快速发作和延长的止痛持续时间
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申请号： US14479129申请日： 2014-09-05
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公开(公告)号： US09539328B2公开(公告)日： 2017-01-10
- 发明人: Krishna Devarakonda , Michael J. Giuliani , Vishal K. Gupta , Ralph A. Heasley , Susan Shelby
- 申请人： MALLINCKRODT LLC
- 申请人地址： US MO Hazelwood
- 专利权人： MALLINCKRODT LLC
- 当前专利权人： MALLINCKRODT LLC
- 当前专利权人地址： US MO Hazelwood
- 代理机构： Mayer Brown LLP
- 主分类号： A61K9/20
- IPC分类号： A61K9/20 ; A61K47/10 ; A61K51/12 ; A61K9/24 ; A61K31/167 ; A61K31/485
摘要：
The present disclosure provides an extended release pharmaceutical composition comprising hydrocodone and acetaminophen that provides a rapid onset of analgesia, and reduced levels of acetaminophen near the end of the dosing interval. Also provided are methods for reducing the risk of acetaminophen-induced hepatic damage in a subject being treated with an acetaminophen containing composition, as well as methods for treating pain in a subject in need thereof.
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