Invention Grant
US09540614B2 Method for generating cancer stem cells from immortalized cell lines
有权
从永生化细胞系产生癌症干细胞的方法
- Patent Title: Method for generating cancer stem cells from immortalized cell lines
- Patent Title (中): 从永生化细胞系产生癌症干细胞的方法
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Application No.: US14222697Application Date: 2014-03-24
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Publication No.: US09540614B2Publication Date: 2017-01-10
- Inventor: Sunghoi Hong , Seung-Ick Oh , Hang-Soo Park
- Applicant: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
- Applicant Address: KR Seoul
- Assignee: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
- Current Assignee: KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION
- Current Assignee Address: KR Seoul
- Agency: Hultquist, PLLC
- Agent Steven J. Hultquist
- Priority: KR10-2013-0121609 20131011
- Main IPC: C12N5/095
- IPC: C12N5/095
Abstract:
A method is described for generating a novel cancer stem cell line that possesses characteristics associated with stem cells, by co-culturing a human immortalized cell line and bone marrow-derived mesenchymal stem cells, and the novel cancer stem cell line established thereby. This method is able to readily generate cancer stem cells that are low in the level of structural chromosomal aberrations and are excellent in oncogenicity, and is effectively applicable to the development of anti-cancer drugs and personalized drugs.
Public/Granted literature
- US20150104864A1 METHOD FOR GENERATING CANCER STEM CELLS FROM IMMORTALIZED CELL LINES Public/Granted day:2015-04-16
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