发明授权
- 专利标题： Capping prone RNA polymerase enzymes and their applications
- 专利标题（中）： 封顶易感RNA聚合酶及其应用
-
申请号： US14598874申请日： 2015-01-16
-
公开(公告)号： US09540671B2公开(公告)日： 2017-01-10
- 发明人: Philippe Jais
- 申请人： EUKARYS
- 申请人地址： FR Evry
- 专利权人： EUKARYS
- 当前专利权人： EUKARYS
- 当前专利权人地址： FR Evry
- 代理机构： Fish & Richardson P.C.
- 优先权： EP10305400 20100416
- 主分类号： C12N9/14
- IPC分类号： C12N9/14 ; C12P19/34 ; C12N9/10 ; C12N9/12 ; A61K38/00
摘要：
The invention provides a chimeric enzyme comprising at least one catalytic domain of a RNA triphosphatase, at least one catalytic domain of a guanylyltransferase, at least one catalytic domain of a N7-guanine methyltransferase, and at least one catalytic domain of a DNA-dependant RNA polymerase. The invention also provides pharmaceutical composition comprising said chimeric enzyme and uses of said chimeric enzyme.