Invention Grant
- Patent Title: Capping prone RNA polymerase enzymes and their applications
- Patent Title (中): 封顶易感RNA聚合酶及其应用
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Application No.: US14598874Application Date: 2015-01-16
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Publication No.: US09540671B2Publication Date: 2017-01-10
- Inventor: Philippe Jais
- Applicant: EUKARYS
- Applicant Address: FR Evry
- Assignee: EUKARYS
- Current Assignee: EUKARYS
- Current Assignee Address: FR Evry
- Agency: Fish & Richardson P.C.
- Priority: EP10305400 20100416
- Main IPC: C12N9/14
- IPC: C12N9/14 ; C12P19/34 ; C12N9/10 ; C12N9/12 ; A61K38/00
Abstract:
The invention provides a chimeric enzyme comprising at least one catalytic domain of a RNA triphosphatase, at least one catalytic domain of a guanylyltransferase, at least one catalytic domain of a N7-guanine methyltransferase, and at least one catalytic domain of a DNA-dependant RNA polymerase. The invention also provides pharmaceutical composition comprising said chimeric enzyme and uses of said chimeric enzyme.
Public/Granted literature
- US20150203888A1 Capping-Prone RNA Polymerase Enzymes and Their Applications Public/Granted day:2015-07-23
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