Invention Grant
US09546186B2 Non-invasive diagnostic agents of cancer and methods of diagnosing cancer, especially leukemia and lymphoma 有权
癌症的非侵入性诊断剂和诊断癌症的方法,特别是白血病和淋巴瘤

  • Patent Title: Non-invasive diagnostic agents of cancer and methods of diagnosing cancer, especially leukemia and lymphoma
  • Patent Title (中): 癌症的非侵入性诊断剂和诊断癌症的方法,特别是白血病和淋巴瘤
  • Application No.: US14451916
    Application Date: 2014-08-05
  • Publication No.: US09546186B2
    Publication Date: 2017-01-17
  • Inventor: Jeffrey P. NorenbergRichard S. Larson
  • Applicant: STC.UNM
  • Applicant Address: US NM Albuquerque
  • Assignee: STC.UNM
  • Current Assignee: STC.UNM
  • Current Assignee Address: US NM Albuquerque
  • Agent Henry D. Coleman; R. Neil Sudol
  • Main IPC: A61K51/00
  • IPC: A61K51/00 A61M36/14 C07F5/00 C07F9/94 A61K49/10 A61K51/04
Non-invasive diagnostic agents of cancer and methods of diagnosing cancer, especially leukemia and lymphoma
Abstract:
The present invention is directed to novel non-invasive diagnostic tools to image cancers, especially, leukemia and non-Hodgkin's lymphomas (NHL) with minimal toxicity in vivo. The present invention represents a clear advance in the art which presently relies on tissue biopsy for diagnoses of these cancers. The novel imaging probe is capable of detecting precancerous cells, as well as their metastatic spread in tissues. This represents a quantum step forward in the diagnosis and staging of NHL using non-invasively molecular imaging techniques. This novel probe will also be useful to monitor patients response to chemotherapy treatments and other interventions or therapies used in the treatment of NHL. Compounds according to the present invention may be used as diagnostic tools for a number of conditions and diseases states as well as therapeutic agents for treating such conditions and disease states.
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