Invention Grant
US09550771B2 Keto-imidazopyridine derivatives as RORc modulators 有权
酮 - 咪唑并吡啶衍生物作为RORc调节剂

  • Patent Title: Keto-imidazopyridine derivatives as RORc modulators
  • Patent Title (中): 酮 - 咪唑并吡啶衍生物作为RORc调节剂
  • Application No.: US14481991
    Application Date: 2014-09-10
  • Publication No.: US09550771B2
    Publication Date: 2017-01-24
  • Inventor: Benjamin FauberAlberto Gobbi
  • Applicant: Genentech, Inc.
  • Applicant Address: US CA South San Francisco
  • Assignee: Genentech, Inc.
  • Current Assignee: Genentech, Inc.
  • Current Assignee Address: US CA South San Francisco
  • Agent Robert C. Hall
  • Main IPC: C07D471/04
  • IPC: C07D471/04 C07D487/04
Keto-imidazopyridine derivatives as RORc modulators
Abstract:
Compounds of the formula I or II: or pharmaceutically acceptable salts thereof, wherein R1 is a group of formula (a), (b), (c); (d) or (e): and m, n, X, Y, R1, R2, R3, R4, Rb and Rc are as defined herein. Also disclosed are methods of making the compounds and using the compounds for treatment of inflammatory diseases such as arthritis.
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