发明授权
- 专利标题： Cryopreservation of apoptotic cancer cells for use in immunotherapy against cancer
- 专利标题（中）： 凋亡癌细胞的冷冻保存用于免疫治疗癌症
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申请号： US14142448申请日： 2013-12-27
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公开(公告)号： US09562219B2公开(公告)日： 2017-02-07
- 发明人: Jitka Fucikova , Lenka Koci , Katerina Pokorna , Iva Truxova , Irena Moserova , Daniela Rozkova , Radek Spisek
- 申请人： SOTIO a.s.
- 申请人地址： CZ Prague
- 专利权人： SOTIO A.S.
- 当前专利权人： SOTIO A.S.
- 当前专利权人地址： CZ Prague
- 代理机构： Leason Ellis LLP.
- 主分类号： C12N5/09
- IPC分类号： C12N5/09 ; A61K35/13 ; A61K39/00 ; A01N1/02
摘要：
Described herein is a reliable method for preparing a potent vaccine useful for immunotherapy comprising the step of cryopreserving a population of cells undergoing immunogenic cell death, and using such cells to activate dendritic cells for use in immunotherapy. In a specific embodiment, the method comprises cryopreserving cancer cells undergoing cell death, which can be used to prepare a pharmaceutical composition for immunotherapy against cancer.
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